Hello,
It’s been a while since I last used Nextclade, and a majority of the sequences I’ve submitted for samples taken between January and April 2025 show a very high number of mutations. The reference sequence used is BA.2.86. Should I change it?
Thanks in advance!
Léa Pilorgé
Hi Léa,
BA.2.86 is the most recent reference sequence on Nextclade and it should be good to use. If you want to see what additional mutations have happened recently, you can make Nextclade display only mutations that occurred since the last clade founder. This can be achieved by selecting the appropriate entry in the drop-down above the sequence view in the results table.
hope this helps,
richard