Search by mutation?

This might be a naive question but is it possible to search the SARS-CoV-2 sequence collection by mutation to determine (1) how many times a mutation has been observed before and (2) when a mutation was first observed and (3) in which geographic regions is that mutation prevalent.

I have a local copy of the GISAID sequences / metadata but haven’t yet learned enough to use ncov competently. I don’t know if this is something that’s done trivially through the web app or requires scripting it myself.

Thanks,
Alex